Recent Publications


Staphylococcal superantigens stimulate epithelial cells through CD40 to produce chemokines. Schlievert, P, Cahill, M, Hostager, B, Brosnahan, A, Klingelhutz, A, Gourronc, F, Bishop, G and Leung, D. mBio, in press, 2019.

DC Nlrc4 regulates influenza A virus-specific CD4 T cell responses through FasL expression. Hornick, EE, Dagvadorj, J, Zacharias, Z, Miller, AM, Langlois, R, Chen, P, Legge, K, Bishop, G, Cassel, S and Sutterwala, F. J Clin Invest, in press, 2019.   


TRAF3 regulation of inhibitory signaling pathways in B and T lymphocytes by kinase and phosphatase localization. Wallis, AM and Bishop, GA. J Leuk Biol 103:1089-1098 , 2018. PMID: 29345428

TRAF3 as a multifaceted regulator of B lymphocyte survival and activation. Bishop, GA, Hostager, BS and Stunz, LL. Front Immunol, 9:2161, p.1-10, 2018.  PMC6165887. PMID: 30319624

Nlrp12 mediates adverse neutrophil recruitment during influenza virus infection. Hornick, EE, Banoth, B, Miller, AM, Zacharias, ZR, Jain, N, Wilson, ME, Gibson-Corley, KN, Legge, KL, Bishop, GA, Sutterwala, FS and Cassel, SL. J Immunol, 200 (3): 1188-1197, 2018. PMID: 29282312


The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency. Bangalore-Prakash P, Stunz LL, Mambetsariev N, Whillock AL, Hostager BS, Bishop GA. Blood Adv. 2017 Dec 18;1(27):2712-2723. doi: 10.1182/bloodadvances.2017009670. eCollection 2017 Dec 26. PMC5745131

TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22. Wallis AM, Wallace EC, Hostager BS, Yi Z, Houtman JCD, Bishop GA. Sci Rep. 2017 May 18;7(1):2081. doi: 10.1038/s41598-017-02280-4. PMID: 28522807

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TRAF3 deficiency promotes metabolic reprogramming in B cells. Mambetsariev N, Lin WW, Wallis AM, Stunz LL, Bishop GA. Sci Rep. 2016 Oct 18;6:35349. doi: 10.1038/srep35349. PMID: 27752131 


TRAF2 exerts opposing effects on basal and TNFα-induced activation of the classic IKK complex in hematopoietic cells in mice. Zhang L, Blackwell K, Workman LM, Gibson-Corley KN, Olivier AK, Bishop GA, Habelhah H. J Cell Sci. 2016 Apr 1;129(7):1455-67. doi: 10.1242/jcs.180554. PMID: 26872784 


Nuclear TRAF3 is a negative regulator of CREB in B cells. Mambetsariev N, Lin WW, Stunz LL, Hanson BM, Hildebrand JM, Bishop GA. Proc Natl Acad Sci U S A. 2016 Jan 26;113(4):1032-7. doi: 10.1073/pnas.1514586113. PMID: 26755589 

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The adaptor protein TRAF3 inhibits interleukin-6 receptor signaling in B cells to limit plasma cell development. Lin WW, Yi Z, Stunz LL, Maine CJ, Sherman LA, Bishop GA.
Sci Signal. 2015 Sep 1;8(392):ra88. doi: 10.1126/scisignal.aaa5157. PMID: 26329582 


Systems-wide analysis of BCR signalosomes and downstream phosphorylation and ubiquitylation. Satpathy S, Wagner SA, Beli P, Gupta R, Kristiansen TA, Malinova D, Francavilla C, Tolar P, Bishop GA, Hostager BS, Choudhary C. Mol Syst Biol. 2015 Jun 2;11(6):810. doi: 10.15252/msb.20145880. PMID: 26038114 


Induction of an altered CD40 signaling complex by an antagonistic human monoclonal antibody to CD40. Bankert KC, Oxley KL, Smith SM, Graham JP, de Boer M, Thewissen M, Simons PJ, Bishop GA. J Immunol. 2015 May 1;194(9):4319-27. doi: 10.4049/jimmunol.1402903. PMID: 25795759 

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A new model of LMP1-MYC interaction in B cell lymphoma. Ontiveros EP, Halwani A, Stunz LL, Kamberos N, Olivier AK, Janz S, Bishop GA. Leuk Lymphoma. 2014 Dec;55(12):2917-23. doi: 10.3109/10428194.2014.900762. PMID: 24605938 


Regulatory role of CD40 in obesity-induced insulin resistance. Yi Z, Bishop GA. Adipocyte. 2014 Oct 30;4(1):65-9. doi: 10.4161/adip.32214. PMID: 26167405


The adaptor TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating signaling via the receptor for IL-2. Yi Z, Lin WW, Stunz LL, Bishop GA.
Nat Immunol. 2014 Sep;15(9):866-74. doi: 10.1038/ni.2944. PMID: 25029551 


CD40-mediated maintenance of immune homeostasis in the adipose tissue microenvironment. Yi Z, Stunz LL, Bishop GA. Diabetes. 2014 Aug;63(8):2751-60. doi: 10.2337/db13-1657. PMID: 24647739 


TRAF3 regulates homeostasis of CD8+ central memory T cells. Yi Z, Stunz LL, Lin WW, Bishop GA. PLoS One. 2014 Jul 10;9(7):e102120. doi: 10.1371/journal.pone.0102120. PMID: 25010048 


TRAF6 is a critical regulator of LMP1 functions in vivo. Arcipowski KM, Stunz LL, Bishop GA. Int Immunol. 2014 Mar;26(3):149-58. doi: 10.1093/intimm/dxt052. PMID: 24170780 


TRAF5 negatively regulates TLR signaling in B lymphocytes. Buchta CM, Bishop GA. J Immunol. 2014 Jan 1;192(1):145-50. doi: 10.4049/jimmunol.1301901. PMID: 24259503 

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TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development. Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, Takahama Y, Hodes RJ. Proc Natl Acad Sci U S A. 2013 Dec 24;110(52):21107-12. doi: 10.1073/pnas.1314859111. PMID: 24324158 


A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes. Lin WW, Hildebrand JM, Bishop GA. Front Immunol. 2013 Dec 20;4:477. doi: 10.3389/fimmu.2013.00477. PMID: 24391649  


Context-specific BAFF-R signaling by the NF-κB and PI3K pathways. Jellusova J, Miletic AV, Cato MH, Lin WW, Hu Y, Bishop GA, Shlomchik MJ, Rickert RC. Cell Rep. 2013 Nov 27;5(4):1022-35. doi: 10.1016/j.celrep.2013.10.022. PMID: 24239354 


Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells. Han SS, Tompkins VS, Son DJ, Kamberos NL, Stunz LL, Halwani A, Bishop GA, Janz S. Biochem Biophys Res Commun. 2013 Jul 12;436(4):660-5. doi: 10.1016/j.bbrc.2013.06.012. PMID: 23764397 


TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells. Yi Z, Stunz LL, Bishop GA. J Exp Med. 2013 Jun 3;210(6):1079-86. doi: 10.1084/jem.20122135. PMID: 23650438 

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