Recent Publications

 

Bishop, G. A. (2024). The JI-Changing with the Times. J Immunol 212 (1) 1-2. DOI: 10.4049/jimmunol.2300763. PMID: 38118105.

Sun, F., Cheng, Y., Wanchai, V., Mery, D., Xu, H., Gai, D., Siegel, E. R., Bailey, C., Ashby, T. C., Al Hadidi, S., Schinke, C., Thanendrarajan, S., Zangari, M., van Rhee, F., Janz, S., Bishop, G. A., Tricot, G., Shaughnessy, Jr, J. D. & Zhan, F. (2024) Bi-specific BCMA/CD24 CAR-T cells targeting both proliferative and tumor initiating cells and enhancing phagocytosis in myeloma. Nature Communications 15, 615 (2024). 

Rogers, K. J., Richards, P. T., Zacharias, Z. R., Stunz, L. L., Vijay, R., Butler, N. S., Legge, K. L., Bishop, G. A. & Maury, W. J. (2023). CD40 signaling in mice elicits a broad antiviral response early during acute viral infection with RNA viruses. Viruses 15 (6) 1353

Berton, R. R., McGonagill, P. W., Jensen, I. J., Ybarra, T. K., Bishop, G. A., Harty, J. T., Griffith, T. S. & Badovinac, V. P. (2023) Sepsis leads to lasting changes in phenotype and function of naïve CD8 T cells. PLOS Pathogens 19 (10) e1011720.

Hornick, E. L., Stunz, L. L., Sabree, S., Wu, X., Witzig, T. E. & Bishop, G. A. (2022). The tumor suppressor protein TRAF3 modulates GSK3 activity and susceptibility of B lymphoma cells to GSK3 Inhibition. Cancers (Basel) 14 (20) 5029.

Hornick, E. L., Wallis, A. M. & Bishop, G. A. (2022). TRAF3 enhances type I interferon receptor signaling in T cells by modulating the phosphatase PTPN22. Sci Signal 15 (753) eabn5507.

Rae, W., Sowerby, J. M., Voehoeven, D., Youssef, M., Kotagiri, P., Savinykh, N., Coomber, E. L., Boneparth, A., Chan, A., Gong, C., Jansen, M. H., du Long, R., Santilli, G., Simeoni, I., Stephens, J., Wu, K., Zinicola, M., Allen, H. L., Baxendale, H., Gkrania-Klotsas, E., Mendoza, S. C., Yamazaki-Nakashimada, M. A., Ruiz, L. B., Rojas-Maruri, C. M., Reyes, S. O., Lyons, P. A., Williams, A. P., Hodson, D. J., Bishop, G. A., Thrasher, A. J., Thomas, D. C., Murphy, M. P., Vyse, T. J., Milner, J. D., Kuijpers, T. W., Smith, K. G. & Kumararatne, D. (2022). Immunodeficiency, autoimmunity, and increased risk of B cell malignancy in humans with TRAF3 mutations. Sci Immunol 7 (74) eabn3800

Hornick E, Wallis, A, Bishop GA, Sci Signal 15(753):eabn 5507, 2022. TRAF3 enhances type I interferon receptor signaling in T cells by modulating the phosphatase PTPN22. 

Michaud D, Mirlekar B, Bishop GA, Pylayeva-Gupta Y, Front Immunol. 12:745873, 2022. B cell receptor signaling and PKD2 support regulatory B cell function in pancreatic cancer.

Gurley JM, Gmyrek GB, Hargis EA, Bishop GA, Carr DJ J, Elliott MH, Cells 10:2068, 2021. The Chx10-Traf3 knockout mouse as a viable model to study neuronal immune regulation.

Li H, Hostager BS, Arkee T, Bishop GA,  J Biol Chem297:101097, 2021. Multiple mechanisms for TRAF3-mediated regulation of the T cell costimulatory receptor GITR.

Arkee T, Hostager BS, Houtman JC D, Bishop GA., J Immunol. 207:322-332, 2021. TRAF3 in T cells restrains negative regulators of LAT to promote TCR/CD28 signaling.

Whillock, A.L., Ybarra, T. and Bishop, GA,  J. Biol Chem. 296:100465, 2021. TRAF3 restrains BCR signaling in normal and malignant B cells.

Oxley, K.L., Hanson, B.M., Zani, A.N. and Bishop, GA, Cancer Immunol. Immunother. 70:3093-3103, 2021. Activated B lymphocytes and tumor cell lysate as an effective cellular cancer vaccine.

Whillock, A.L., Ybarra, T. and Bishop, G. J. Biol Chem. 2021. TNF receptor-associated factor 3 restrains B-cell receptor signaling in normal and malignant B cells.

Munroe, M.E., Anderson, R.R., Gross, T.F., Stunz, L.L., Bishop, GA. and James, J.A..  Front. Immunol. 11:Article 606936, p. 1-20, 2021. EBV functional mimicry: Pathogenicity of oncogenic LMP1 in SLE and autoimmunity. 

Rogers, K.J., Shtanko, O., Stunz, L.L., Mallinger, L.N., Arkee, T., Schmidt, M.E., Bohan, D., Brunton, B., White, J.M., Varga, S.M., Butler, N.S., Bishop, GA, and Maury, W. J. Leuk. Biol (epub May 22): 1-17, 2020. Frontline Science (Highlighted article): CD40 signaling restricts RNA virus replication in macrophages, leading to rapid innate immune control of acute virus infection.

Whillock, A., Mambetsariev, N., Lin. W.W., Stunz, L.L. and Bishop, GA  Nature Scientific Reports 9:12884, p. 1-12, 2019. TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells.

Schlievert, P, Cahill, M, Hostager, B, Brosnahan, A, Klingelhutz, A, Gourronc, F, Bishop, GA and Leung, D. mBio,  2019. Staphylococcal superantigens stimulate epithelial cells through CD40 to produce chemokines.

Hornick, EE, Dagvadorj, J, Zacharias, Z, Miller, AM, Langlois, R, Chen, P, Legge, K, BBishop, GA, Cassel, S and Sutterwala, F. J Clin Invest, 2019.   DC Nlrc4 regulates influenza A virus-specific CD4 T cell responses through FasL expression.

Wu, X., Stenson, M., Abeykoon, J., Nowakowski, K.E., Zhang, L., Lawson, J., Wellik, L., Li, Y., Krull, J., Wenzl, K., Novak, A.J., Ansell, S., Bishop, GA, Billadeau, D.D., Peng, K.W., Giles, F., Schmitt, D.M., and Witzig, T.E. Blood. 134:363-373,  2019. Targeting GSK3 for therapeutic benefit in lymphoma.

Gao, M., Bai, H., Jethava, Y., Wu, Y. Zhu, Y., Yang, Y., Xia, J., Cao, H., Franqui-Machin, R., Nadiminti, K., Thomas, G.S., Salama, M.E., Altevogt, P.,Tomasson, M., Janz,S., Shi, J., Chen, L., Frech, I., Tricot, G., and Zhan, F.J. Natl. Cancer Inst. 112:507, 2019.  Identification and characterization of tumor-initiating cells in multiple myeloma.

Wallis, AM and Bishop, GA,. J Leuk Biol 103:1089-1098 , 2018. PMID: 29345428, TRAF3 regulation of inhibitory signaling pathways in B and T lymphocytes by kinase and phosphatase localization.

Bishop, GA, Hostager, BS and Stunz, LL. Front Immunol, 9:2161, p.1-10, 2018.  PMC6165887. PMID: 30319624. TRAF3 as a multifaceted regulator of B lymphocyte survival and activation. 

Hornick, EE, Banoth, B, Miller, AM, Zacharias, ZR, Jain, N, Wilson, ME, Gibson-Corley, KN, Legge, KL, Bishop, GA, Sutterwala, FS and Cassel, SL. J Immunol, 200 (3): 1188-1197, 2018. PMID: 29282312. Nlrp12 mediates adverse neutrophil recruitment during influenza virus infection. 

Bangalore-Prakash P, Stunz LL, Mambetsariev N, Whillock AL, Hostager BS, Bishop GA. Blood Adv. 2017 Dec 18;1(27):2712-2723. doi: 10.1182/bloodadvances.2017009670. eCollection 2017 Dec 26. PMC5745131. The oncogenic membrane protein LMP1 sequesters TRAF3 in B-cell lymphoma cells to produce functional TRAF3 deficiency.

Wallis AM, Wallace EC, Hostager BS, Yi Z, Houtman JCD, Bishop GA. Sci Rep. 2017 May 18;7(1):2081. doi: 10.1038/s41598-017-02280-4. PMID: 28522807. TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN2.