Welcome to the Bishop Lab
Back row, L to R: Tiffany Ybarra, Bruce Hostager, Shakoora Sabree, Kyp Oxley, Emma Hornick
Front row, L to R: Nicole Hines, Gail Bishop, Tina Arkee, Alejandra Garcia Orosco
We are interested in the molecular mechanisms which underlie the processes of lymphocyte activation and tolerance. Our particular areas of current focus are in lymphocyte signaling and interactions between innate and adaptive immune receptors.
The following is a summary of key projects ongoing in the lab:
1. How does TRAF3 regulate B lymphocyte survival and activation? How does TRAF3 act as a tumor suppressor in B cell cancers? How does loss of TRAF3 in aging and chronic inflammation contribute to autoimmunity and predispose to malignancy?
2. What roles does TRAF3 play in regulation of signaling and effector functions of T lymphocytes?
3. How does CD40 signaling contribute to early resistance of cells to infection with Ebola and SARS-CoV-2 viruses?
Learn More about our Research
Positions and Affiliations